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Welcome to the
PANGEA Calculator

The PANGEA Model predicts your risk of progression from MGUS or SMM to multiple myeloma 

Do You Have MGUS or SMM?

Learn more about monoclonal gammopathy of undetermined

significance (MGUS) and smoldering multiple myeloma (SMM)

The PROMISE Study is a national effort to test people who are at higher risks of MGUS, SMM, and multiple myeloma. The goal of the PROMISE Study is to find these disease states early & understand why some people develop them while others do not.

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Learn more at www.promisestudy.org

The PCROWD Study is a national effort to collect data from patients with MGUS or SMM. The goal is to understand why some people develop these conditions & why some patients with MGUS or SMM develop multiple myeloma while others do not.

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Learn more at www.pcrowd.org

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Research and development of the PANGEA Model by Annie Cowan and Federico Ferrari, PhD

Leadership provided by Irene Ghobrial, MD and Lorenzo Trippa, PhD

Design assistance for the PANGEA Calculator by Daniel Schwartz, PhD 

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To learn more about the PANGEA Model, please read our publication in Lancet Haematology

© 2023 by the Ghobrial Lab | Dana-Farber Cancer Institute | Boston, MA | USA 

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